EaseUS OS2Go and EaseUS Todo Backup support Windows To Go creation. Hasleo WinToUSB, the world's first third-party Windows To Go tool, is the best alternative to EaseUS OS2Go and the built-in Windows To Go Creator in EaseUS Todo Backup.
EaseUS OS2Go is software developed by EaseUS to create Windows To Go, which supports installing Windows from an ISO file to a USB or cloning an existing Windows to USB drives.

EaseUS Todo Backup is a powerful, reliable, and secure Windows backup solution providing Windows OS, disks/partitions, and files backup features. Additionally, it is a Windows disk cloning tool for Windows, disks/partitions cloning. The Windows To Go Creator built into EaseUS Todo Backup is an advanced Windows cloning option. It clones Windows from an internal disk to a USB drive and allows the OS to boot correctly from the drive. It functions similarly to Microsoft's Windows To Go Creator Wizard, but it does not support creating Windows To Go directly from ISO/WIM/ESD files.

To be honest, the EaseUS OS2Go and Windows To Go Creator built into EaseUS Todo Backup are great Windows To Go solutions, offering a nice graphical interface and high success rates. However, they have the following shortcomings:
As mentioned above, EaseUS OS2Go is a paid tool, and the Windows To Go Creator built into EaseUS Todo Backup (it is also a paid feature) can only clone an existing Windows to a USB drive as Windows To Go. It does not support creating Windows To Go from ISO/WIM/ESD/VHD(X) files. If EaseUS Windows To Go Creator doesn't meet your needs, you may need an alternative. Here, we recommend you to try Hasleo WinToUSB, it is the world’s first third-party Windows To Go Creator that perfectly solves all the problems mentioned above.
Step 1. Connect the USB drive to your computer, then download, install, and run Hasleo WinToUSB. Click the "Windows To Go USB" option.

Step 2. Click "Select installation source" => "Browse image file". Select the Windows installation ISO file from the dialog box as your source. Alternatively, choose a CD/DVD drive with a Windows installation media.

Step 3. Hasleo WinToUSB will scan for and list the available Windows editions. Please select the edition you want to install.

Step 4. Click "Select destination drive", then choose the target drive from the pop-up list. If Hasleo WinToUSB fails to detect the drive, click the
button to initiate drive recognition.

Step 5. Select your preferred partition scheme and installation mode. Optionally, you may specify additional drives or enable BitLocker encryption for the Windows To Go drive, then click "Proceed".

* Tips:
Step 6. After clicking "Proceed", a confirmation dialog will appear asking whether to continue formatting the drive. Click "Yes" if you accept the operation.

Step 7. After clicking "Yes", WinToUSB initiates Windows installation on the destination drive.

Step 8. The installation will take some time; please be patient. After installation, restart the computer and enter UEFI/BIOS settings to boot from the USB drive.

Step 9. A standard Windows installation requires completing all setup steps during the first boot. Afterward, you can install applications and copy files, etc.

A: Hasleo WinToUSB offers a free version that allows you to create Windows To Go from ISO/WIM/ESD files. The paid Professional version adds additional features like cloning existing Windows to USB and BitLocker encryption support.
A: Yes, WinToUSB supports creating Windows To Go directly from Windows ISO, WIM, ESD, SWM, VHD(X), and DBI files, which EaseUS OS2Go does not support.
A: Yes, WinToUSB supports BitLocker encryption to protect your Windows To Go data. This is a key feature that EaseUS OS2Go and EaseUS Windows To Go Creator do not offer.
A: WinToUSB offers several advantages: free version available, supports ISO/WIM/ESD/VHD(X) file sources, supports BitLocker encryption, creates VHD(X)-based Windows To Go, and does not require certified USB drives.
A: Yes, with WinToUSB Professional, you can clone an existing Windows installation to a USB drive as Windows To Go, similar to EaseUS Windows To Go Creator but with additional features.
As the best free alternative to EaseUS OS2Go and Windows To Go Creator built into EaseUS Todo Backup, not only can you use Hasleo WinToUSB to create Windows To Go from ISO/WIM/ESD/VHD(X) files, but also you can encrypt the Windows TO Go USB drive with BitLocker to protect your data. With the premium version, you can also clone an existing Windows to a USB drive as Windows To Go.
If you are looking for an alternative to EaseUS Todo Backup to back up or clone Windows OS, disks/partitions, we recommended trying the free Windows backup software Hasleo Backup Suite Free.